Amikacin sulfate salt, aminoglycoside antibiotic

Code: A2324-5G D2-231

Application

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibio...


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Application

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .

Biochem/physiol Actions

Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

Antibacterial spectrum: Gram-negative and gram-positive bacteria.

General description

Chemical structure: aminoglycoside

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Aminoglycoside antibiotic. Derivative of kanamycin.

Packaging

5 g in glass bottle

Quality

Amikacin:Sulfate ratio 1:1.8

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria, mycobacteria
biological sourcesynthetic
colorwhite to off-white
concentration691-806 µg/mg (dry)
formpowder
InChI keyHIBICIOPDUTNRR-BOEHXBESSA-N
InChI1S/C22H43N5O13.H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);(H2,1,2,3,4)/t6-,7+,8+,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;/m0./s1
mode of actionprotein synthesis | interferes
Quality Level200
SMILES stringOS(O)(=O)=O.NCC[C@@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
storage temp.2-8°C
Cas Number149022-22-0
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